MTCO3P28

Across TCGA pan-cancer cohorts, MTCO3P28 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MTCO3P28’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MTCO3P28 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MTCO3P28 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KICH, KIRC, and LUAD are the cancer types where MTCO3P28 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO3P28 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.041	.011	4	view →
KIRC	Male	All	−0.058	.011	2	view →
LUAD	All	II,III,IV	+0.030	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MTCO3P28–KICH

Open the KICH breakdown →