Q-omics provides the consensus-scored MTCO3P28 profile across patient tissues and cancer cell-line models. MTCO3P28 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in THYM. Among the 18 cancer types available for tumor–normal comparison, MTCO3P28 is differentially expressed in 3, with the highest sampling consensus in KICH. Additionally, MTCO3P28 RNA expression shows 4,709 significant gene co-expression associations, with the highest sampling consensus in PCPG. Together, these results highlight THYM, KICH, and PCPG as cancer lineages where MTCO3P28 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTCO3P28 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTCO3P28 survival associations across molecular data types. MTCO3P28 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTCO3P28 RNA expression–survival associations across cancer types. High MTCO3P28 expression shows unfavorable associations in THYM, LUAD, SKCM, KIRP and MESO, but favorable associations in CESC. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THYM as the clearest survival context for MTCO3P28 RNA expression.
This table summarizes MTCO3P28 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MTCO3P28. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTCO3P28 shows lower tumor expression in KIRC and higher tumor expression in KICH and LUAD. The KICH box plot shows higher MTCO3P28 RNA expression in tumor versus normal tissue (log2 FC = +0.041, t-test p = .011).
This table shows molecular features associated with MTCO3P28 in patient tissues and cancer cell lines. In patient samples, MTCO3P28 shows the broadest associations at the RNA and protein expression levels, with PCPG recurring as the lineage with the largest associated feature set.
