MTCO2P4

Across TCGA patient cohorts, MTCO2P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,396 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MTCO2P4-associated GO terms across cancer lineages are Negative regulation of peptidyl-serine phosphorylation, Positive regulation of transmembrane transport, and Regulation of generation of precursor metabolites and energy. Each is linked with MTCO2P4 in more than 8 cancer types. Because this analysis shows association rather than direction, both MTCO2P4-to-partner and partner-to-MTCO2P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of peptidyl-serine phosphorylation grouped by MTCO2P4-low versus MTCO2P4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO2P4→partner) and Y-score (partner→MTCO2P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of peptidyl-serine phosphorylation →	+0.058	+0.261	<.001	<.001	3	9
STAD	Positive regulation of transmembrane transport →	+0.040	+0.298	<.001	<.001	3	9
STAD	Regulation of generation of precursor metabolites and energy →	+0.068	+0.281	<.001	<.001	3	9
STAD	Negative regulation of RNA catabolic process →	+0.076	+0.301	<.001	<.001	3	9
STAD	Intrinsic apoptotic signaling pathway by p53 class mediator →	+0.079	+0.240	<.001	<.001	3	8
STAD	Carbohydrate catabolic process →	+0.069	+0.264	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,396 associations by consensus.

Negative regulation of peptidyl-serine phosphorylation by MTCO2P4 expression — STAD

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