MTCO2P4

Across TCGA pan-cancer cohorts, MTCO2P4 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTCO2P4 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MTCO2P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO2P4 expression acts as an unfavorable survival marker.

THCA, BLCA, and HNSC are the cancer types where MTCO2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.750	0.945	<.001	126	view →
BLCA	OS	Tertile	IV	0.308	0.604	<.001	81	view →
HNSC	OS	Tertile	II,III,IV	0.205	0.720	<.001	72	view →
ESCA	OS	Tertile	All	0.464	0.902	.004	36	view →
COAD	DFS	Tertile	III,IV	0.028	0.649	<.001	27	view →
KICH	DFS	Tertile	All	0.264	0.860	<.001	21	view →
PAAD	OS	Tertile	II,III,IV	0.326	0.590	.046	18	view →
ACC	DFS	Tertile	All	0.066	0.623	.006	18	view →
SARC	DFS	Tertile	All	0.181	0.500	.035	12	view →
KIRC	DFS	Tertile	IV	0.179	0.363	.042	6	view →
KIRP	OS	Tertile	All	0.824	0.953	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTCO2P4–THCA (OS)

Open the THCA breakdown →