MTCO1P8

Across TCGA pan-cancer cohorts, MTCO1P8 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MTCO1P8 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MTCO1P8 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO1P8 expression acts as an unfavorable survival marker, although some lineages such as LUSC and ACC show a favorable association.

KIRC, CESC, and READ are the cancer types where MTCO1P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.424	0.694	.008	54	view →
CESC	OS	Tertile	II,III,IV	0.400	0.768	.005	54	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	39	view →
GBM	DFS	Tertile	All	0.128	0.267	.002	36	view →
UCS	DFS	Tertile	IV	0.192	0.776	<.001	36	view →
LUSC	DFS	Tertile	All	0.883	0.626	.013	27	view →
BRCA	OS	Tertile	III,IV	0.333	0.576	.007	24	view →
ACC	DFS	Tertile	All	0.902	0.607	.027	21	view →
SKCM	DFS	Tertile	II,III,IV	0.159	0.245	.021	18	view →
PCPG	DFS	Tertile	All	0.800	0.944	.002	18	view →
UVM	DFS	Tertile	III,IV	0.079	0.635	.021	9	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MTCO1P8–KIRC (DFS)

Open the KIRC breakdown →