MTCO1P53

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MTCO1P53 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,072 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MTCO1P53-associated proteins across cancer lineages are SLIRP, DAP3, and MAPKAPK2. Each is linked with MTCO1P53 in more than 2 cancer types. Because this analysis shows association rather than direction, both MTCO1P53-to-partner and partner-to-MTCO1P53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTCO1P53 versus SLIRP in BRCA, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCO1P53→partner) and Y-score (partner→MTCO1P53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASLIRP →+0.463+1.716<.001.00433
BRCADAP3 →+0.376+1.521<.001.00133
OVMAPKAPK2 →-0.380-2.785<.001<.00133
BRCANUDT2 →-0.347-1.997<.001<.00132
OVRBM17_S222 →-0.555-2.060.004.00332
OVRBM3_S147 →-0.950-2.430<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,072 associations by consensus.

MTCO1P53 vs SLIRP — BRCA

Per-sample scatter of MTCO1P53 vs SLIRP in BRCA (Pearson r = 0.34).

Explore this scatter interactively →

Exploration