MTCO1P49

Across TCGA pan-cancer cohorts, MTCO1P49 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MTCO1P49 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MTCO1P49 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTCO1P49 expression acts as an unfavorable survival marker, although some lineages such as SARC and LGG show a favorable association.

KIRC, BRCA, and STAD are the cancer types where MTCO1P49 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.483	0.680	<.001	100	view →
BRCA	DFS	Tertile	IV	0.175	0.730	.005	45	view →
STAD	OS	Tertile	II,III,IV	0.583	0.713	.007	30	view →
GBM	OS	Tertile	All	0.085	0.422	<.001	27	view →
PRAD	OS	Tertile	All	0.785	0.896	.006	24	view →
SKCM	OS	Tertile	IV	0.234	0.666	.007	21	view →
CESC	OS	Tertile	II,III,IV	0.616	0.841	.017	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
THYM	DFS	Tertile	III,IV	0.205	0.772	.032	9	view →
PAAD	OS	Tertile	II,III,IV	0.382	0.577	.039	9	view →
ESCA	OS	Tertile	All	0.504	0.903	.038	9	view →
ACC	DFS	Tertile	II,III,IV	0.363	0.663	.035	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MTCO1P49–KIRC (OS)

Open the KIRC breakdown →