MTCO1P49

Across TCGA pan-cancer cohorts, MTCO1P49 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MTCO1P49’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MTCO1P49 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO1P49 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.

BRCA, THCA, and KICH are the cancer types where MTCO1P49 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO1P49 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.004	.025	2	view →
THCA	Female	All	−0.029	.015	1	view →
KICH	All	All	+0.023	.022	1	view →
KIRC	Female	All	+0.016	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MTCO1P49–BRCA

Open the BRCA breakdown →