MTCO1P42

Across TCGA pan-cancer cohorts, MTCO1P42 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MTCO1P42 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher MTCO1P42 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MTCO1P42 expression acts as an unfavorable survival marker, although some lineages such as ACC and BLCA show a favorable association.

CHOL, ACC, and BLCA are the cancer types where MTCO1P42 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	All	0.114	0.521	<.001	90	view →
ACC	OS	Tertile	All	0.944	0.698	.001	60	view →
BLCA	OS	Median	All	0.573	0.363	.004	56	view →
BRCA	OS	Tertile	III,IV	0.758	0.865	.009	50	view →
COAD	OS	Tertile	III,IV	0.634	0.864	.001	41	view →
KICH	DFS	Tertile	All	1.000	0.610	.012	35	view →
KIRP	OS	Median	All	0.966	0.575	.001	31	view →
LGG	OS	Quartile	All	0.964	0.838	<.001	25	view →
DLBC	DFS	Quartile	All	0.414	0.940	.002	24	view →
KIRC	DFS	Quartile	III,IV	0.748	0.585	.023	18	view →
ESCA	OS	Median	II,III,IV	0.778	0.582	.005	16	view →
LUAD	DFS	Median	All	0.454	0.273	.011	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MTCO1P42–CHOL (DFS)

Open the CHOL breakdown →