MTCO1P42

Across TCGA pan-cancer cohorts, MTCO1P42 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MTCO1P42’s most consistent transcriptional readouts.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where MTCO1P42 RNA is repressed in tumor relative to normal tissue. In most cancer types MTCO1P42 is over-expressed in tumor, although a few such as PAAD and LUSC show the opposite, repressed pattern.

PAAD, BLCA, and LUSC are the cancer types where MTCO1P42 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MTCO1P42 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
PAAD	Female	All	−0.370	.043	2	view →
BLCA	Female	All	+0.146	.047	2	view →
LUSC	Male	II,III,IV	−0.040	.006	2	view →
KICH	All	All	+0.532	.007	1	view →
KIRC	All	All	−0.086	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MTCO1P42–PAAD

Open the PAAD breakdown →