MTCL1

Across TCGA patient cohorts, MTCL1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,392 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MTCL1-associated genes across cancer lineages are GACAT2, MEI1, and TMEM158. Each is linked with MTCL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MTCL1-to-partner and partner-to-MTCL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MTCL1 versus GACAT2 in CCRCC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTCL1→partner) and Y-score (partner→MTCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GACAT2 →	+1.142	+0.498	<.001	<.001	3	8
LSCC	MEI1 →	-0.866	-0.467	<.001	.001	3	4
LSCC	TMEM158 →	+1.197	+0.463	<.001	<.001	3	4
CCRCC	SPIRE1 →	+0.619	+0.562	<.001	<.001	3	4
BRCA	TBX3 →	+1.344	+0.497	<.001	<.001	3	4
HNSC	RALBP1 →	+0.591	+0.496	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,392 associations by consensus.

MTCL1 vs GACAT2 — CCRCC

Explore this scatter interactively →