MTA3

Across TCGA patient cohorts, MTA3 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MTA3-associated genes across cancer lineages are PAI-1 and S6_pS240_S244. Each is linked with MTA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MTA3-to-partner and partner-to-MTA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAI-1 grouped by MTA3-low versus MTA3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MTA3→partner) and Y-score (partner→MTA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PAI-1 →	-0.386	-2.999	.031	.035	3	1
UCEC	S6_pS240_S244 →	+0.711	+3.321	<.001	.010	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PAI-1 by MTA3 expression — UCEC

Explore this box plot interactively →