MT3

Across TCGA patient cohorts, MT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,109 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MT3-associated GO terms across cancer lineages are Oxidative phosphorylation, Cellular response to zinc ion, and ATP biosynthetic process. Each is linked with MT3 in more than 18 cancer types. Because this analysis shows association rather than direction, both MT3-to-partner and partner-to-MT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxidative phosphorylation grouped by MT3-low versus MT3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT3→partner) and Y-score (partner→MT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Oxidative phosphorylation →	+0.072	+0.195	<.001	<.001	3	19
SCLC	Cellular response to zinc ion →	+0.203	+2.659	<.001	<.001	3	16
STAD	ATP biosynthetic process →	+0.051	+0.193	<.001	<.001	3	16
ESCA	Proton motive force-driven ATP synthesis →	+0.063	+0.246	.003	<.001	2	17
STAD	ATP metabolic process →	+0.069	+0.198	<.001	<.001	2	17
UCS	Peroxisome fission →	+0.057	+1.866	.003	.006	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,109 associations by consensus.

Oxidative phosphorylation by MT3 expression — STAD

Explore this box plot interactively →