MT3

Across TCGA cell cohorts, MT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,482 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MT3-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, ATP synthesis coupled electron transport, and Mitochondrial ATP synthesis coupled electron transport. Each is linked with MT3 in more than 8 cancer types. Because this analysis shows association rather than direction, both MT3-to-partner and partner-to-MT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven ATP synthesis grouped by MT3-low versus MT3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT3→partner) and Y-score (partner→MT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Proton motive force-driven ATP synthesis →	+0.078	+1.042	<.001	.001	3	9
OVARY	ATP synthesis coupled electron transport →	+0.081	+0.606	.001	.009	3	9
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.081	+0.606	.001	.009	3	9
OVARY	Aerobic electron transport chain →	+0.079	+0.606	.001	.009	2	9
OVARY	Proton motive force-driven mitochondrial ATP synthesis →	+0.080	+0.648	.001	.005	3	8
OVARY	ATP biosynthetic process →	+0.075	+0.632	.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,482 associations by consensus.

Proton motive force-driven ATP synthesis by MT3 expression — CNS

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