Across TCGA patient cohorts, MT1M protein abundance is significantly associated with the RNA expression of many other genes, with 3,423 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MT1M-associated genes across cancer lineages are MT1F, PALM2AKAP2, and MT1G. Each is linked with MT1M in more than 3 cancer types. Because this analysis shows association rather than direction, both MT1M-to-partner and partner-to-MT1M results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT1M→partner) and Y-score (partner→MT1M) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MT1F →	+1.960	+2.054	.001	<.001	3	4
BRCA	PALM2AKAP2 →	+0.840	+1.628	<.001	.002	3	3
UCEC	MT1G →	+3.377	+1.996	<.001	.001	3	2
UCEC	MT1E →	+1.851	+1.204	.001	.001	3	2
CCRCC	NT5DC2 →	-0.601	-0.771	.001	.001	3	2
CCRCC	SIRPB3P →	+0.879	+0.971	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,423 associations by consensus.

Exploration

MT1M survival (RNA) · tumor vs normal (RNA) · all MT1M data types