MT1IP

Across TCGA pan-cancer cohorts, MT1IP RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MT1IP data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MT1IP RNA is associated with better overall survival. In most high-consensus cancer types, elevated MT1IP expression acts as an unfavorable survival marker, although some lineages such as MESO and THCA show a favorable association.

MESO, STAD, and THCA are the cancer types where MT1IP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.533	0.317	.007	45	view →
STAD	DFS	Median	II,III,IV	0.500	0.683	.001	41	view →
THCA	DFS	Quartile	III,IV	0.902	0.506	.005	38	view →
LAML	DFS	Tertile	All	0.215	0.602	.005	18	view →
UCS	OS	Tertile	IV	0.225	0.569	.041	18	view →
ESCA	DFS	Quartile	All	0.515	0.293	.005	14	view →
READ	DFS	Quartile	II,III,IV	0.200	0.579	.008	14	view →
KICH	DFS	Tertile	IV	0.269	0.784	.045	9	view →
SKCM	DFS	Tertile	All	0.463	0.186	.003	9	view →
COAD	DFS	Median	III,IV	0.543	0.710	.024	9	view →
ACC	DFS	Tertile	IV	0.793	0.152	.026	9	view →
KIRP	OS	Quartile	All	0.353	0.786	.007	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MT1IP–MESO (OS)

Open the MESO breakdown →