MT1HL1

Across TCGA patient cohorts, MT1HL1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MT1HL1-associated genes across cancer lineages are Monocytes, CD4+ Tcm, and Smooth muscle. Each is linked with MT1HL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MT1HL1-to-partner and partner-to-MT1HL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by MT1HL1-low versus MT1HL1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT1HL1→partner) and Y-score (partner→MT1HL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Monocytes →	+0.072	+6.734	<.001	.018	3	2
HNSC	CD4+ Tcm →	+0.015	+5.468	<.001	.043	3	1
UCEC	Smooth muscle →	+0.181	+2.818	.018	.037	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Monocytes by MT1HL1 expression — COAD

Explore this box plot interactively →