MT1HL1

Across TCGA cell cohorts, MT1HL1 RNA expression is significantly associated with the mutation status of many other genes, with 124 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MT1HL1-associated genes across cancer lineages are HERC1, SLC26A7, and DIDO1. Each is linked with MT1HL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MT1HL1-to-partner and partner-to-MT1HL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HERC1 grouped by MT1HL1-low versus MT1HL1-high in BLOOD_Leukemia.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT1HL1→partner) and Y-score (partner→MT1HL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HERC1 →	+2.244	+0.126	.001	<.001	3	2
BLOOD_Leukemia	SLC26A7 →	+4.922	+0.419	.009	<.001	3	2
CNS	DIDO1 →	+4.035	+0.090	.006	<.001	3	2
LUNG_NSCLC_LUAD	HK3 →	+3.681	+0.065	.009	<.001	3	2
LUNG_NSCLC_LUAD	PTCHD3 →	+3.944	+0.074	.006	<.001	3	2
LUNG_NSCLC_LUAD	F8 →	+3.681	+0.065	.009	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 124 associations by consensus.

HERC1 by MT1HL1 expression — BLOOD_Leukemia

Explore this box plot interactively →