Across TCGA pan-cancer cohorts, MT1F Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MT1F data layer compared with 22 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher MT1F Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MT1F expression acts as an unfavorable survival marker.

ESCA are the cancer types where MT1F Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	All	0.141	0.700	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: MT1F tumor-vs-normal RNA expression · all MT1F data types