Across TCGA pan-cancer cohorts, MT1F mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MT1F data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MT1F mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MT1F expression acts as an unfavorable survival marker.

CCRCC, LSCC, and PDAC are the cancer types where MT1F mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	III,IV	0.080	0.985	.024	13	view →
LSCC	OS	Median	All	0.767	1.000	.015	3	view →
PDAC	DFS	Median	IV	0.190	0.749	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MT1F tumor-vs-normal RNA expression · all MT1F data types