Across TCGA patient cohorts, MT1F mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MT1F-associated genes across cancer lineages are TIMM9P1, MEMO1P3, and PAICSP6. Each is linked with MT1F in more than 1 cancer types. Because this analysis shows association rather than direction, both MT1F-to-partner and partner-to-MT1F results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT1F→partner) and Y-score (partner→MT1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TIMM9P1 →	+0.208	+4.979	<.001	.009	3	1
SKCM	MEMO1P3 →	+0.162	+5.292	<.001	.006	3	1
SKCM	PAICSP6 →	+0.046	+5.224	<.001	.007	3	1
SKCM	RN7SL443P →	+0.259	+5.037	<.001	.009	3	1
SKCM	RN7SL418P →	+0.186	+5.097	<.001	.008	3	1
SKCM	DNAJB8-AS1 →	+0.034	+5.224	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

MT1F survival (RNA) · tumor vs normal (RNA) · all MT1F data types