Across TCGA patient cohorts, MT-TY RNA expression is significantly associated with the protein abundance of many other proteins, with 7,907 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MT-TY-associated proteins across cancer lineages are CD2AP_S256, MTDH_S298, and MAP1B_S992. Each is linked with MT-TY in more than 2 cancer types. Because this analysis shows association rather than direction, both MT-TY-to-partner and partner-to-MT-TY results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TY→partner) and Y-score (partner→MT-TY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CD2AP_S256 →	+1.086	+1.250	<.001	<.001	3	3
OV	MTDH_S298 →	-1.328	-1.639	<.001	<.001	3	3
OV	MAP1B_S992 →	+0.877	+1.153	.007	.008	3	3
COAD	SPAG9_S203 →	+0.639	+1.108	.008	.002	3	3
BRCA	SF3B1_T426 →	+0.452	+0.959	<.001	<.001	3	3
OV	ZYX_S344 →	-0.778	-1.207	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,907 associations by consensus.

Exploration

MT-TY survival (RNA) · tumor vs normal (RNA) · all MT-TY data types