Across TCGA patient cohorts, MT-TT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,908 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MT-TT-associated GO terms across cancer lineages are Mitochondrial electron transport, ubiquinol to cytochrome c, Mitochondrial electron transport, NADH to ubiquinone, and Proton transmembrane transport. Each is linked with MT-TT in more than 15 cancer types. Because this analysis shows association rather than direction, both MT-TT-to-partner and partner-to-MT-TT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TT→partner) and Y-score (partner→MT-TT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.038	+1.415	<.001	<.001	3	16
LGG	Mitochondrial electron transport, NADH to ubiquinone →	+0.023	+0.734	<.001	<.001	3	15
ACC	Proton transmembrane transport →	+0.019	+1.349	<.001	<.001	3	15
DLBC	Establishment of mitotic sister chromatid cohesion →	-0.088	-1.953	.003	.002	1	16
LGG	ATP synthesis coupled electron transport →	+0.022	+0.850	<.001	<.001	3	14
THYM	Neuronal stem cell population maintenance →	-0.058	-1.776	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,908 associations by consensus.

Exploration

MT-TT survival (RNA) · tumor vs normal (RNA) · all MT-TT data types