Across TCGA pan-cancer cohorts, MT-TS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MT-TS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MT-TS1 RNA is repressed in tumor relative to normal tissue. In most cancer types MT-TS1 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

BLCA and THCA are the cancer types where MT-TS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MT-TS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−0.186	.036	2	view →
THCA	All	All	+0.063	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: MT-TS1 RNA expression & survival · all MT-TS1 data types