Across TCGA patient cohorts, MT-TG RNA expression is significantly associated with the go_rna of many other GO terms, with 5,880 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MT-TG-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Cellular respiration, and Oxidative phosphorylation. Each is linked with MT-TG in more than 13 cancer types. Because this analysis shows association rather than direction, both MT-TG-to-partner and partner-to-MT-TG results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TG→partner) and Y-score (partner→MT-TG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Multi-pass transmembrane protein insertion into ER membrane →	+0.031	+0.229	<.001	<.001	3	14
KIRP	Cellular respiration →	+0.019	+0.480	<.001	<.001	3	12
CHOL	Oxidative phosphorylation →	+0.027	+0.592	.001	.009	1	14
CHOL	Aerobic respiration →	+0.021	+0.762	.004	.004	1	14
LGG	Proton transmembrane transport →	+0.018	+0.593	<.001	<.001	3	11
KIRC	NADH dehydrogenase complex assembly →	+0.024	+0.277	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,880 associations by consensus.

Exploration

MT-TG survival (RNA) · tumor vs normal (RNA) · all MT-TG data types