Across TCGA patient cohorts, MT-TC RNA expression is significantly associated with the go_rna of many other GO terms, with 7,071 significant associations in total. OV shows the largest number of these associations.

The most reproducible MT-TC-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Meiotic chromosome condensation, and Positive regulation of chromosome segregation. Each is linked with MT-TC in more than 30 cancer types. Because this analysis shows association rather than direction, both MT-TC-to-partner and partner-to-MT-TC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TC→partner) and Y-score (partner→MT-TC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Positive regulation of chromosome condensation →	-0.138	-1.751	<.001	<.001	3	31
DLBC	Meiotic chromosome condensation →	-0.136	-1.793	<.001	<.001	3	29
DLBC	Positive regulation of chromosome segregation →	-0.094	-1.810	<.001	<.001	3	28
DLBC	Interstrand cross-link repair →	-0.065	-1.535	<.001	<.001	3	28
DLBC	Regulation of centriole replication →	-0.071	-1.932	<.001	<.001	3	28
DLBC	Regulation of chromosome condensation →	-0.107	-1.796	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,071 associations by consensus.

Exploration

MT-TC survival (RNA) · tumor vs normal (RNA) · all MT-TC data types