Across TCGA cell cohorts, MT-ND6 mutation is significantly associated with the RNA expression of many other genes, with 137 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible MT-ND6-associated genes across cancer lineages are OR13H1, NAT8B, and KRTAP5-4. Each is linked with MT-ND6 in more than 2 cancer types. Because this analysis shows association rather than direction, both MT-ND6-to-partner and partner-to-MT-ND6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND6→partner) and Y-score (partner→MT-ND6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	OR13H1 →	+0.075	+4.169	<.001	.008	3	3
BONE	NAT8B →	+0.038	+4.000	<.001	.008	3	2
BONE	KRTAP5-4 →	+0.025	+4.169	<.001	.008	3	2
BONE	KCNK16 →	+0.023	+4.307	<.001	.004	3	2
PANCREAS	TAAR8 →	+0.014	+4.029	<.001	.007	3	2
BLOOD_Myeloma	CCDC179 →	+0.025	+3.285	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 137 associations by consensus.

Exploration

MT-ND6 survival (RNA) · tumor vs normal (RNA) · all MT-ND6 data types