Across TCGA cell cohorts, MT-ND4L RNA expression is significantly associated with the RNA expression of many other genes, with 10,353 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MT-ND4L-associated genes across cancer lineages are MT-ND3, MT-ND4, and MT-CO3. Each is linked with MT-ND4L in more than 19 cancer types. Because this analysis shows association rather than direction, both MT-ND4L-to-partner and partner-to-MT-ND4L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND4L→partner) and Y-score (partner→MT-ND4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MT-ND3 →	+1.387	+1.001	<.001	<.001	3	20
PANCREAS	MT-ND4 →	+1.702	+1.344	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	MT-CO3 →	+1.231	+1.153	<.001	<.001	3	20
PANCREAS	MT-CYB →	+1.384	+1.328	<.001	<.001	3	19
OESOPHAGUS	MT-CO1 →	+1.240	+0.799	<.001	<.001	3	19
LIVER	MT-ND2 →	+1.632	+1.297	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,353 associations by consensus.

Exploration

MT-ND4L survival (RNA) · tumor vs normal (RNA) · all MT-ND4L data types