Across TCGA patient cohorts, MT-ND2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,916 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MT-ND2-associated genes across cancer lineages are IL12B, PXMP4, and TMEM115. Each is linked with MT-ND2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MT-ND2-to-partner and partner-to-MT-ND2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND2→partner) and Y-score (partner→MT-ND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IL12B →	+0.806	+1.259	<.001	.001	3	3
BRCA	PXMP4 →	+1.420	+0.684	.009	<.001	3	2
OV	TMEM115 →	+0.397	+0.628	.001	.002	3	2
BRCA	TCTA →	+0.890	+0.706	.001	.008	3	2
CCRCC	CLDN7 →	+0.850	+0.384	.009	.001	3	2
CCRCC	ERICH2 →	-0.820	-0.488	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,916 associations by consensus.

Exploration

MT-ND2 survival (RNA) · tumor vs normal (RNA) · all MT-ND2 data types