MT-ND1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MT-ND1 mutation is significantly associated with the RNA expression of many other genes, with 634 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MT-ND1-associated genes across cancer lineages are C17orf98, RANBP3, and OR52H1. Each is linked with MT-ND1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MT-ND1-to-partner and partner-to-MT-ND1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-ND1→partner) and Y-score (partner→MT-ND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTC17orf98 →+0.040+3.584<.001.00533
BLOOD_LeukemiaRANBP3 →+0.464+3.518<.001<.00133
BONEOR52H1 →+0.024+4.000<.001.00832
BONEGAGE2E →+2.344+4.000.001.00832
STOMACHCHST10 →+1.791+3.070.002.00832
SOFT_TISSUEKRT37 →+0.125+4.459<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 634 associations by consensus.

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