Across TCGA patient cohorts, MT-CYB protein abundance is significantly associated with the protein abundance of many other proteins, with 1,615 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MT-CYB-associated proteins across cancer lineages are FAM3B, TPK1, and INPP5A. Each is linked with MT-CYB in more than 1 cancer types. Because this analysis shows association rather than direction, both MT-CYB-to-partner and partner-to-MT-CYB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CYB→partner) and Y-score (partner→MT-CYB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	FAM3B →	+0.949	+0.755	.002	.003	3	2
BRCA	TPK1 →	-0.559	-1.675	.002	.002	3	2
PDAC	INPP5A →	+0.967	+0.647	<.001	.003	3	2
CCRCC	SNTB2_S208 →	+0.678	+0.861	<.001	<.001	3	1
CCRCC	SREBF2_S469 →	+0.526	+0.706	<.001	<.001	3	1
CCRCC	PAH_S16 →	+1.102	+0.788	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,615 associations by consensus.

Exploration

MT-CYB survival (RNA) · tumor vs normal (RNA) · all MT-CYB data types