Across TCGA cell cohorts, MT-CYB RNA expression is significantly associated with the go_rna of many other GO terms, with 2,618 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MT-CYB-associated GO terms across cancer lineages are Metaphase chromosome alignment, Cell junction assembly, and Maintenance of unfolded protein. Each is linked with MT-CYB in more than 7 cancer types. Because this analysis shows association rather than direction, both MT-CYB-to-partner and partner-to-MT-CYB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CYB→partner) and Y-score (partner→MT-CYB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Metaphase chromosome alignment →	-0.052	-0.523	.008	.009	3	8
UPPER_AERODIGESTIVE_TRACT	Cell junction assembly →	+0.083	+1.545	<.001	<.001	3	7
LARGE_INTESTINE	Maintenance of unfolded protein →	+0.146	+1.002	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Establishment of mitotic sister chromatid cohesion →	-0.102	-1.215	.009	.002	3	7
UPPER_AERODIGESTIVE_TRACT	Telomere maintenance via telomerase →	-0.125	-1.549	.004	.002	3	7
LUNG_SCLC	Negative regulation of microtubule depolymerization →	-0.121	-0.865	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,618 associations by consensus.

Exploration

MT-CYB survival (RNA) · tumor vs normal (RNA) · all MT-CYB data types