MT-CO3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MT-CO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,797 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MT-CO3-associated GO terms across cancer lineages are Negative regulation of microtubule depolymerization, Telomeric 3' overhang formation, and DAMP biosynthetic process. Each is linked with MT-CO3 in more than 8 cancer types. Because this analysis shows association rather than direction, both MT-CO3-to-partner and partner-to-MT-CO3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CO3→partner) and Y-score (partner→MT-CO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINNegative regulation of microtubule depolymerization →-0.078-0.715<.001.00139
UPPER_AERODIGESTIVE_TRACTTelomeric 3' overhang formation →-0.134-1.291.001.00429
OVARYDAMP biosynthetic process →-0.108-0.707.002.00438
UPPER_AERODIGESTIVE_TRACTRegulation of chromosome segregation →-0.091-1.194.008.00238
BLOOD_LymphomaPositive regulation of RNA splicing →-0.071-0.640.003.00938
OVARYPurine deoxyribonucleoside monophosphate biosynthetic process →-0.108-0.707.002.00438
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,797 associations by consensus.

Exploration