MT-CO3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MT-CO3 mutation is significantly associated with the RNA expression of many other genes, with 82 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MT-CO3-associated genes across cancer lineages are FEZF2, NEUROD6, and SKOR2. Each is linked with MT-CO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MT-CO3-to-partner and partner-to-MT-CO3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CO3→partner) and Y-score (partner→MT-CO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCFEZF2 →+0.018+3.000.001.00632
URINARY_TRACTNEUROD6 →+0.022+4.087<.001.00932
URINARY_TRACTSKOR2 →+0.037+4.087.001.00932
BLOOD_MyelomaCA4 →+0.201+3.716<.001.00532
BLOOD_LymphomaCIDEA →+0.122+5.247<.001.00132
STOMACHTEX48 →+0.327+2.857<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

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