MT-CO3

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MT-CO3 mutation is significantly associated with the mutation status of many other genes, with 386 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MT-CO3-associated genes across cancer lineages are MT-CYB, MT-ATP6, and MT-ND2. Each is linked with MT-CO3 in more than 5 cancer types. Because this analysis shows association rather than direction, both MT-CO3-to-partner and partner-to-MT-CO3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CO3→partner) and Y-score (partner→MT-CO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSMT-CYB →+3.415+3.415.002.00216
CNSMT-ATP6 →+4.614+4.614.006.00614
LARGE_INTESTINEMT-ND2 →+2.292+3.501<.001<.00114
STOMACHMT-ND5 →+1.955+2.781.009.00914
CNSIGFN1 →+2.877+4.360.006.00614
LARGE_INTESTINEMT-CO1 →+2.807+2.954.001.00113
Each partner links to its Q-omics profile. Showing the 6 strongest of 386 associations by consensus.

Exploration