Across TCGA cell cohorts, MT-CO2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,223 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MT-CO2-associated GO terms across cancer lineages are Maintenance of unfolded protein, Body fluid secretion, and DAMP biosynthetic process. Each is linked with MT-CO2 in more than 9 cancer types. Because this analysis shows association rather than direction, both MT-CO2-to-partner and partner-to-MT-CO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CO2→partner) and Y-score (partner→MT-CO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Maintenance of unfolded protein →	+0.146	+0.969	<.001	<.001	3	10
BONE	Body fluid secretion →	+0.136	+0.778	<.001	<.001	3	9
LIVER	DAMP biosynthetic process →	-0.112	-1.294	.002	.008	2	9
LIVER	Purine deoxyribonucleoside monophosphate biosynthetic process →	-0.112	-1.294	.002	.008	2	9
CNS	Nail development →	+0.321	+0.733	.005	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Cell cycle G1/S phase transition →	-0.063	-1.401	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,223 associations by consensus.

Exploration

MT-CO2 survival (RNA) · tumor vs normal (RNA) · all MT-CO2 data types