MSTO1

Across TCGA patient cohorts, MSTO1 mutation is significantly associated with the RNA expression of many other genes, with 1,794 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MSTO1-associated genes across cancer lineages are RNU6-31P, TRAJ12, and RNF19BPY. Each is linked with MSTO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSTO1-to-partner and partner-to-MSTO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-31P grouped by MSTO1-low versus MSTO1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSTO1→partner) and Y-score (partner→MSTO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-31P →	+0.426	+1.690	<.001	.007	3	2
UCEC	TRAJ12 →	+0.541	+2.051	<.001	.001	3	2
UCEC	RNF19BPY →	+0.015	+3.738	<.001	.009	3	2
UCEC	SNORA84 →	+0.659	+2.055	<.001	<.001	3	2
UCEC	RRM1-AS1 →	+0.327	+2.172	<.001	.002	3	2
LUAD	SLC25A5P4 →	+0.059	+4.990	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,794 associations by consensus.

RNU6-31P by MSTO1 expression — UCEC

Explore this box plot interactively →