MSTO1

Across TCGA cell cohorts, MSTO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,222 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MSTO1-associated GO terms across cancer lineages are DNA topological change, Subtelomeric heterochromatin formation, and Regulation of protein sumoylation. Each is linked with MSTO1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MSTO1-to-partner and partner-to-MSTO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA topological change grouped by MSTO1-low versus MSTO1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSTO1→partner) and Y-score (partner→MSTO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA topological change →	+0.123	+0.824	<.001	.002	3	14
OESOPHAGUS	Subtelomeric heterochromatin formation →	+0.104	+0.810	<.001	.001	3	14
LARGE_INTESTINE	Regulation of protein sumoylation →	+0.122	+0.948	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.182	+0.698	.003	.007	3	13
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.166	+1.032	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA replication proofreading →	+0.185	+1.102	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,222 associations by consensus.

DNA topological change by MSTO1 expression — SOFT_TISSUE

Explore this box plot interactively →