MST1R

Across TCGA pan-cancer cohorts, MST1R mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MST1R data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MST1R mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated MST1R expression acts as an unfavorable survival marker, although some lineages such as UCEC and OV show a favorable association.

UCEC, LSCC, and OV are the cancer types where MST1R mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	1.000	0.564	.024	16	view →
LSCC	OS	Median	All	0.677	0.886	.003	11	view →
OV	DFS	Tertile	All	1.000	0.542	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MST1R–UCEC (OS)

Open the UCEC breakdown →