MSRB2

Across TCGA patient cohorts, MSRB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,546 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MSRB2-associated proteins across cancer lineages are PLEKHA6, DDX39A, and PHYH. Each is linked with MSRB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both MSRB2-to-partner and partner-to-MSRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSRB2 versus PLEKHA6 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRB2→partner) and Y-score (partner→MSRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA6 →	+0.535	+0.429	<.001	<.001	3	5
GBM	DDX39A →	-0.288	-0.556	.001	<.001	3	4
LSCC	PHYH →	+0.457	+0.346	<.001	.001	3	4
LSCC	ARHGAP12 →	+0.276	+0.493	<.001	<.001	3	4
GBM	GDI2 →	+0.368	+0.533	<.001	<.001	3	4
OV	SLC25A19 →	-0.398	-0.442	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,546 associations by consensus.

MSRB2 vs PLEKHA6 — LSCC

Explore this scatter interactively →