MSRA

Across TCGA cell cohorts, MSRA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,551 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MSRA-associated GO terms across cancer lineages are Myotube differentiation, Positive regulation of matrix metallopeptidase secretion, and Regulation of regulatory ncRNA-mediated heterochromatin formation. Each is linked with MSRA in more than 7 cancer types. Because this analysis shows association rather than direction, both MSRA-to-partner and partner-to-MSRA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myotube differentiation grouped by MSRA-low versus MSRA-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSRA→partner) and Y-score (partner→MSRA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Myotube differentiation →	+0.089	+0.737	<.001	.004	3	7
BLOOD_Myeloma	Positive regulation of matrix metallopeptidase secretion →	-0.227	-1.778	<.001	.003	3	7
URINARY_TRACT	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.112	+0.867	.001	.004	2	8
URINARY_TRACT	Negative regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.112	+0.867	.001	.004	2	8
KIDNEY	Deoxyribonucleotide metabolic process →	+0.140	+0.942	.004	.004	3	7
LIVER	L-serine transport →	+0.144	+1.476	.002	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,551 associations by consensus.

Myotube differentiation by MSRA expression — KIDNEY

Explore this box plot interactively →