MSR1

Across TCGA patient cohorts, MSR1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,782 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MSR1-associated genes across cancer lineages are LILRB1, CD33, and MS4A6A. Each is linked with MSR1 in more than 8 cancer types. Because this analysis shows association rather than direction, both MSR1-to-partner and partner-to-MSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MSR1 versus LILRB1 in GBM, with a Pearson correlation of 0.77.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSR1→partner) and Y-score (partner→MSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LILRB1 →	+1.032	+0.870	<.001	<.001	3	9
GBM	CD33 →	+0.972	+0.902	<.001	<.001	3	9
GBM	MS4A6A →	+1.384	+0.860	<.001	<.001	3	9
GBM	NCKAP1L →	+1.221	+0.922	<.001	<.001	3	9
GBM	SIGLEC9 →	+1.287	+0.935	<.001	<.001	3	9
GBM	DOCK2 →	+1.192	+0.883	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,782 associations by consensus.

MSR1 vs LILRB1 — GBM

Explore this scatter interactively →