MSR1

Across TCGA cell cohorts, MSR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,359 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MSR1-associated GO terms across cancer lineages are Positive regulation of cholesterol storage, Chloride transmembrane transport, and Monoatomic anion transport. Each is linked with MSR1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MSR1-to-partner and partner-to-MSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cholesterol storage grouped by MSR1-low versus MSR1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MSR1→partner) and Y-score (partner→MSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of cholesterol storage →	-0.252	-1.209	<.001	<.001	3	11
OVARY	Chloride transmembrane transport →	-0.054	-1.205	.004	<.001	3	8
OVARY	Monoatomic anion transport →	-0.050	-0.908	<.001	.004	3	7
SOFT_TISSUE	Regulation of toll-like receptor 9 signaling pathway →	-0.111	-1.248	<.001	.001	3	6
SKIN	Positive regulation of plasma membrane bounded cell projection assembly →	+0.036	+0.949	<.001	.007	3	6
BREAST	Positive regulation of stress granule assembly →	+0.092	+0.379	.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,359 associations by consensus.

Positive regulation of cholesterol storage by MSR1 expression — OVARY

Explore this box plot interactively →