MSGN1

Across TCGA patient cohorts, MSGN1 mutation is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MSGN1-associated genes across cancer lineages are PINCR, RNU7-81P, and TSPY24P. Each is linked with MSGN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSGN1-to-partner and partner-to-MSGN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PINCR grouped by MSGN1-low versus MSGN1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSGN1→partner) and Y-score (partner→MSGN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PINCR →	+0.616	+3.798	<.001	.009	3	2
COAD	RNU7-81P →	+0.413	+5.332	<.001	.002	3	2
SKCM	TSPY24P →	+0.068	+4.743	.003	.005	3	2
SKCM	RN7SKP188 →	+0.117	+4.743	<.001	.005	3	2
UCEC	RNU6-5P →	+0.579	+2.619	<.001	.001	3	2
UCEC	DLAT →	+0.661	+3.354	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

PINCR by MSGN1 expression — COAD

Explore this box plot interactively →