MSANTD4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MSANTD4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MSANTD4-associated genes across cancer lineages are C1orf189 and ADAM7. Each is linked with MSANTD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MSANTD4-to-partner and partner-to-MSANTD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf189 grouped by MSANTD4-low versus MSANTD4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSANTD4→partner) and Y-score (partner→MSANTD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEC1orf189 →+0.173+4.054<.001.00431
LARGE_INTESTINEADAM7 →+0.005+3.930<.001.00331
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C1orf189 by MSANTD4 expression — LARGE_INTESTINE

Box plot of C1orf189 in MSANTD4-low vs MSANTD4-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration