MSANTD4

Across TCGA pan-cancer cohorts, MSANTD4 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of MSANTD4’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MSANTD4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MSANTD4 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

HNSC, THCA, and CHOL are the cancer types where MSANTD4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MSANTD4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.926	<.001	12	view →
THCA	Male	III,IV	−1.024	<.001	10	view →
CHOL	All	All	+1.953	<.001	5	view →
KICH	All	All	−0.568	.001	4	view →
COAD	Male	All	+0.444	.003	4	view →
BRCA	Female	All	−0.268	<.001	4	view →
READ	All	III,IV	+0.724	.002	3	view →
LIHC	Female	All	+0.563	.003	3	view →
UCEC	All	All	−0.814	.001	2	view →
LUSC	All	III,IV	−0.725	<.001	2	view →
PRAD	All	All	−0.513	<.001	2	view →
ESCA	All	All	+0.651	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

MSANTD4–HNSC

Open the HNSC breakdown →