MS4A6E

Across TCGA patient cohorts, MS4A6E RNA expression is significantly associated with the protein abundance of many other proteins, with 8,580 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MS4A6E-associated proteins across cancer lineages are HCK, CD53, and PRAM1. Each is linked with MS4A6E in more than 4 cancer types. Because this analysis shows association rather than direction, both MS4A6E-to-partner and partner-to-MS4A6E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MS4A6E versus HCK in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A6E→partner) and Y-score (partner→MS4A6E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HCK →	+0.618	+0.300	<.001	<.001	3	5
GBM	CD53 →	+0.529	+0.324	<.001	.001	3	4
COAD	PRAM1 →	+0.710	+0.225	<.001	.004	3	4
GBM	PRTN3 →	+1.059	+0.352	<.001	.007	3	4
OV	PLEKHO2_S390 →	+0.589	+0.447	.002	.002	3	4
GBM	SKAP2 →	+0.656	+0.284	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,580 associations by consensus.

MS4A6E vs HCK — GBM

Explore this scatter interactively →