MS4A6A

Across TCGA cell cohorts, MS4A6A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,149 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MS4A6A-associated GO terms across cancer lineages are Viral budding, Endosome organization, and Protein dephosphorylation. Each is linked with MS4A6A in more than 4 cancer types. Because this analysis shows association rather than direction, both MS4A6A-to-partner and partner-to-MS4A6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral budding grouped by MS4A6A-low versus MS4A6A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A6A→partner) and Y-score (partner→MS4A6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral budding →	+0.057	+0.076	.006	.008	3	5
BLOOD_Leukemia	Endosome organization →	+0.025	+1.691	.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Protein dephosphorylation →	+0.040	+0.076	.004	.008	3	4
LIVER	Positive regulation of cyclin-dependent protein kinase activity →	+0.149	+0.047	<.001	.001	3	4
OESOPHAGUS	N-terminal protein amino acid acetylation →	+0.127	+0.143	<.001	.002	3	4
BLOOD_Leukemia	Cellular response to thyroid hormone stimulus →	+0.153	+1.812	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,149 associations by consensus.

Viral budding by MS4A6A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →