MS4A12

Across TCGA cell cohorts, MS4A12 RNA expression is significantly associated with the go_rna of many other GO terms, with 540 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MS4A12-associated GO terms across cancer lineages are Geranyl diphosphate metabolic process, SNARE complex disassembly, and Neutral lipid catabolic process. Each is linked with MS4A12 in more than 2 cancer types. Because this analysis shows association rather than direction, both MS4A12-to-partner and partner-to-MS4A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Geranyl diphosphate metabolic process grouped by MS4A12-low versus MS4A12-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A12→partner) and Y-score (partner→MS4A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Geranyl diphosphate metabolic process →	+0.087	+0.034	<.001	.001	3	3
LARGE_INTESTINE	SNARE complex disassembly →	-0.104	-0.045	<.001	.001	3	3
LARGE_INTESTINE	Neutral lipid catabolic process →	+0.053	+0.034	.009	.001	3	3
LARGE_INTESTINE	Acylglycerol catabolic process →	+0.053	+0.034	.009	.001	3	3
SOFT_TISSUE	Alternative mRNA splicing, via spliceosome →	+0.088	+0.083	<.001	.005	3	3
OVARY	Lactone catabolic process →	-0.177	-0.086	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 540 associations by consensus.

Geranyl diphosphate metabolic process by MS4A12 expression — LARGE_INTESTINE

Explore this box plot interactively →