MS4A12

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MS4A12 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MS4A12-associated genes across cancer lineages are MS4A6E. Each is linked with MS4A12 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A12-to-partner and partner-to-MS4A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A6E grouped by MS4A12-low versus MS4A12-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A12→partner) and Y-score (partner→MS4A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCMS4A6E →+0.072+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MS4A6E by MS4A12 expression — LUNG_SCLC

Box plot of MS4A6E in MS4A12-low vs MS4A12-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration